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small animal computed tomography system  (Revvity)


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    Revvity small animal computed tomography system
    Small Animal Computed Tomography System, supplied by Revvity, used in various techniques. Bioz Stars score: 97/100, based on 2088 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/small+animal+computed+tomography+system/Quantum+GX3+microCT/pm41856972-381-5-11
    Average 97 stars, based on 2088 article reviews
    small animal computed tomography system - by Bioz Stars, 2026-09
    97/100 stars

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    In vivo 99m Tc-(HE) 3 -(GPO) <t>9</t> <t>SPECT/CT</t> imaging. (A and B) Illustrative examples of CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images of control (A) and bleomycin-treated (B) mice 3 wk after induction, acquired starting 1 h after tracer injection. (C) Quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by SPECT/CT in control and bleomycin-treated groups. ** P < 0.01, based on Mann–Whitney U test. (D) Ex vivo quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by γ-well counting in control and bleomycin-treated groups 2 h after tracer injection. ** P < 0.01, based on Mann–Whitney U test. (E) Correlation between in vivo SPECT/CT and ex vivo γ-well counting evaluation of 99m Tc-(HE) 3 -(GPO) 9 lung uptake (Spearman r = 0.83). *** P < 0.001, based on 2-tailed test. Inset box shows correlation after excluding outlier (Spearman r = 0.79). ** P < 0.01.
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    Image Search Results


    In vivo 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT imaging. (A and B) Illustrative examples of CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images of control (A) and bleomycin-treated (B) mice 3 wk after induction, acquired starting 1 h after tracer injection. (C) Quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by SPECT/CT in control and bleomycin-treated groups. ** P < 0.01, based on Mann–Whitney U test. (D) Ex vivo quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by γ-well counting in control and bleomycin-treated groups 2 h after tracer injection. ** P < 0.01, based on Mann–Whitney U test. (E) Correlation between in vivo SPECT/CT and ex vivo γ-well counting evaluation of 99m Tc-(HE) 3 -(GPO) 9 lung uptake (Spearman r = 0.83). *** P < 0.001, based on 2-tailed test. Inset box shows correlation after excluding outlier (Spearman r = 0.79). ** P < 0.01.

    Journal: Journal of Nuclear Medicine

    Article Title: Collagen Hybridizing Peptide–Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis

    doi: 10.2967/jnumed.124.268832

    Figure Lengend Snippet: In vivo 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT imaging. (A and B) Illustrative examples of CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images of control (A) and bleomycin-treated (B) mice 3 wk after induction, acquired starting 1 h after tracer injection. (C) Quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by SPECT/CT in control and bleomycin-treated groups. ** P < 0.01, based on Mann–Whitney U test. (D) Ex vivo quantification of 99m Tc-(HE) 3 -(GPO) 9 lung uptake by γ-well counting in control and bleomycin-treated groups 2 h after tracer injection. ** P < 0.01, based on Mann–Whitney U test. (E) Correlation between in vivo SPECT/CT and ex vivo γ-well counting evaluation of 99m Tc-(HE) 3 -(GPO) 9 lung uptake (Spearman r = 0.83). *** P < 0.001, based on 2-tailed test. Inset box shows correlation after excluding outlier (Spearman r = 0.79). ** P < 0.01.

    Article Snippet: Animals were imaged 1 h after tracer injection on a small-animal–dedicated SPECT/CT scanner (U-SPECT 4 CT; MILabs), as described previously with minor modification.

    Techniques: In Vivo, Single Photon Emission Computed Tomography, Imaging, Control, Injection, MANN-WHITNEY, Ex Vivo

    Specificity of 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal. (A) Illustrative examples of in vivo CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) SCR and 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images in bleomycin-treated mouse 3 wk after induction. (B) Quantification of 99m Tc-(HE) 3 -GPO SCR and 99m Tc-(HE) 3 -(GPO) 9 lung uptake by SPECT/CT. ** P < 0.01, based on Wilcoxon matched-pair test.

    Journal: Journal of Nuclear Medicine

    Article Title: Collagen Hybridizing Peptide–Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis

    doi: 10.2967/jnumed.124.268832

    Figure Lengend Snippet: Specificity of 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal. (A) Illustrative examples of in vivo CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) SCR and 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images in bleomycin-treated mouse 3 wk after induction. (B) Quantification of 99m Tc-(HE) 3 -GPO SCR and 99m Tc-(HE) 3 -(GPO) 9 lung uptake by SPECT/CT. ** P < 0.01, based on Wilcoxon matched-pair test.

    Article Snippet: Animals were imaged 1 h after tracer injection on a small-animal–dedicated SPECT/CT scanner (U-SPECT 4 CT; MILabs), as described previously with minor modification.

    Techniques: Single Photon Emission Computed Tomography, In Vivo

    Lung histology in saline and bleomycin-treated mice. (A and B) Illustrative examples of Masson trichrome (top) and R-CHP (bottom) staining of control (A) and bleomycin-treated (B) mice 3 wk after induction. (C) Quantification of collagen content by Masson trichrome staining in control and bleomycin-treated lungs. * P < 0.05, based on Mann–Whitney U test). (D) Correlation between lung 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal and collagen content by Masson trichrome staining (Spearman r = 0.85). *** P < 0.001. Inset box shows correlation after excluding outlier (Spearman r = 0.69). ** P < 0.05. (E) Quantification of denatured collagen content by R-CHP staining in control and bleomycin lungs. * P < 0.01, based on Mann–Whitney U test. (F) Correlation between lung 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal and denatured collagen content by R-CHP staining (Spearman r = 0.64). * P < 0.05. A.U. = arbitrary units.

    Journal: Journal of Nuclear Medicine

    Article Title: Collagen Hybridizing Peptide–Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis

    doi: 10.2967/jnumed.124.268832

    Figure Lengend Snippet: Lung histology in saline and bleomycin-treated mice. (A and B) Illustrative examples of Masson trichrome (top) and R-CHP (bottom) staining of control (A) and bleomycin-treated (B) mice 3 wk after induction. (C) Quantification of collagen content by Masson trichrome staining in control and bleomycin-treated lungs. * P < 0.05, based on Mann–Whitney U test). (D) Correlation between lung 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal and collagen content by Masson trichrome staining (Spearman r = 0.85). *** P < 0.001. Inset box shows correlation after excluding outlier (Spearman r = 0.69). ** P < 0.05. (E) Quantification of denatured collagen content by R-CHP staining in control and bleomycin lungs. * P < 0.01, based on Mann–Whitney U test. (F) Correlation between lung 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT signal and denatured collagen content by R-CHP staining (Spearman r = 0.64). * P < 0.05. A.U. = arbitrary units.

    Article Snippet: Animals were imaged 1 h after tracer injection on a small-animal–dedicated SPECT/CT scanner (U-SPECT 4 CT; MILabs), as described previously with minor modification.

    Techniques: Saline, Staining, Control, MANN-WHITNEY, Single Photon Emission Computed Tomography

    Serial 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT imaging in pulmonary fibrosis. (A) Illustrative examples of in vivo CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images in bleomycin-treated mouse 3 and 10 wk after induction. (B) Quantification of lung tracer uptake in control and bleomycin-treated mice 3 and 8–10 wk after induction. * P < 0.05, based on Wilcoxon matched-pair test. (C) Illustrative examples of Masson trichrome lung staining in control (left) and bleomycin-treated (right) mice 8 wk after induction. (D) Quantification of collagen content by Masson trichrome staining in control and bleomycin-treated lungs 8–10 wk after induction. ns = nonsignificant, based on Mann–Whitney U test.

    Journal: Journal of Nuclear Medicine

    Article Title: Collagen Hybridizing Peptide–Based Radiotracers for Molecular Imaging of Collagen Turnover in Pulmonary Fibrosis

    doi: 10.2967/jnumed.124.268832

    Figure Lengend Snippet: Serial 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT imaging in pulmonary fibrosis. (A) Illustrative examples of in vivo CE-CT (top) and fused 99m Tc-(HE) 3 -(GPO) 9 SPECT/CT (bottom) images in bleomycin-treated mouse 3 and 10 wk after induction. (B) Quantification of lung tracer uptake in control and bleomycin-treated mice 3 and 8–10 wk after induction. * P < 0.05, based on Wilcoxon matched-pair test. (C) Illustrative examples of Masson trichrome lung staining in control (left) and bleomycin-treated (right) mice 8 wk after induction. (D) Quantification of collagen content by Masson trichrome staining in control and bleomycin-treated lungs 8–10 wk after induction. ns = nonsignificant, based on Mann–Whitney U test.

    Article Snippet: Animals were imaged 1 h after tracer injection on a small-animal–dedicated SPECT/CT scanner (U-SPECT 4 CT; MILabs), as described previously with minor modification.

    Techniques: Single Photon Emission Computed Tomography, Imaging, In Vivo, Control, Staining, MANN-WHITNEY